A complete hormonal, metabolic, and cardiovascular assessment for patients on Testosterone Replacement Therapy — built to support precise dosing, safety monitoring, and long-term optimization.

Rythm Labs provides an in-depth evaluation of the biomarkers that matter most for patients on TRT. This panel covers core hormone levels alongside thyroid, cardiovascular, metabolic, hematological, and organ function markers — giving providers a complete picture to support safe, effective, and individualized therapy.

Includes the following tests:

Hormone Balance

Total & Free Testosterone (Calculated) – Measures total testosterone and calculates free testosterone for accurate therapy monitoring.
Sex Hormone-Binding Globulin (SHBG) – Evaluates the protein that binds testosterone, helping determine how much hormone is actually available for the body to use.
Estradiol (E2) – Monitors estrogen levels to help detect hormonal imbalances and guide therapy adjustments.

Thyroid Function

TSH (Thyroid-Stimulating Hormone) – Assesses thyroid signaling, which can influence overall hormonal balance and energy.
Free T3 – Measures active thyroid hormone driving metabolism and energy levels.

Cardiovascular Health

ApoB – A leading predictive marker for cardiovascular risk, particularly relevant during TRT.
Total, LDL & HDL Cholesterol – Full lipid profile to monitor cardiovascular health.
LDL-C / ApoB Ratio – Assesses cholesterol particle size for a deeper view of cardiovascular risk.
hsCRP – Detects low-grade systemic inflammation not captured by a standard lipid panel.
Remnant Cholesterol & Total Cholesterol/HDL Ratio – Additional markers for cardiovascular risk stratification.

Metabolic Health

Fructosamine – Tracks average blood sugar control over recent weeks.
Triglycerides & Triglycerides/HDL Ratio – Evaluates fat metabolism and early signs of insulin resistance.
Vitamin D – Supports hormone production, immune function, and mood.
Ferritin – Monitors iron storage, which affects energy levels and red blood cell production.
Uric Acid – Reflects metabolic and cellular health.
Albumin – Indicates nutritional and protein status.

Blood Health

Hemoglobin & Hematocrit – Monitors red blood cell count and blood thickness, a key safety check while on TRT.

Kidney & Liver Function

Creatinine – Evaluates kidney filtration and function.
ALP (Alkaline Phosphatase) – Assesses liver and bone health.
GGT – Sensitive marker for early changes in liver health.

At-home blood collection kit includes:

1x single-use collection device – simple, reliable at-home collection
1x collection tube – secure sample storage for transport
Heat pack, alcohol swab, bandage, bio bag – everything needed for a clean, safe draw
Prepaid FedEx return label – easy, prepaid shipping back to the lab

Shipping & Logistics

Kits ship FedEx 2-Day directly to the patient
Return shipping via FedEx Priority Overnight to the lab
FedEx pickup available directly from home

Digital Patient Experience

Guided, step-by-step virtual assistant via QR code
Real-time kit tracking with delivery confirmation in the patient portal

Turnaround Time

Results typically available within ~36 hours of laboratory receipt

Rythm Labs gives providers a thorough, well-rounded assessment of hormonal, metabolic, cardiovascular, and organ health — supporting individualized TRT dosing decisions and helping patients track meaningful progress over time.